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Name:ML277
| Chemical structure | Code NO. |
MT1087 |
 |
Name |
ML277 |
Synonym |
ML-277; ML 277; CID-53347902; CID53347902; CID 53347902 | |
CAS NO. |
1401242-74-7 | |
Chemical Formula |
C23H25N3O4S2 | |
MW |
471.59 | |
Purity |
>98% | |
Solubility(R.T.: 25℃) |
100 mM in DMSO | |
Stability |
- 20℃, 2 years |
Availability and price
We offer big discount for bulk quantities. If you have any other questions or needs, please send email to sales@meditechbs.com. We’ll reply you asap.
Description
ML277(CID53347902) is a novel, potent and selective K(v)7.1 (KCNQ1) potassium channel activator with EC50 of 270 nM.
IC50 value: 270 nM (EC50) [1]
Target: K(v)7.1 activator
ML277 was shown to be highly selective against other KCNQ channels (>100-fold selectivity versus KCNQ2 and KCNQ4) as well as against the distantly related hERG potassium channel.
IC50 value: 270 nM (EC50) [1]
Target: K(v)7.1 activator
ML277 was shown to be highly selective against other KCNQ channels (>100-fold selectivity versus KCNQ2 and KCNQ4) as well as against the distantly related hERG potassium channel.
References
Attention
Sold for research purposes only; not for human use of any kind.
